Sign up for a conference on chemical biology, organised by WG2 of the ChemLife theme.

When: 3-4 September 2024

Where: LINXS (Scheelevägen 19, Lund), workshop room on the 5th floor and ESS

Registration information: Please register latest 26/8 to join the tour at ESS

Description

One of the defining features of chemical biology is the design and application of small-molecule ligands as chemical probes to study biology. Chemical probes that are designed to interact with a specific macromolecule or small-biomolecule - with high affinity and selectivity - can facilitate the study of phenotypes associated with the macromolecule or small-biomolecule and its function. This working group is interested in the design and application of chemical probes to study the structure and function of biomolecules. This includes the design and use of small molecules for sample design and preparation for X-ray and neutron scattering experiments.

• Programme

  Detailed agenda to follow

  3 September

  9.00    Introduction & Welcome

  9.15    “Developing chemical tools to study Histone Deacetylase enzymes in corepressor complexes” – Dr James Hodgkinson, LISCB

  9.45     “Using aldehydes to treat disease” – Dr Richard Hopkinson, LISCB

  10.15    Morning coffee/fika

  10.45   “Reactive Sulfur Species: biology’s dark matter comes to light” – Dr Christopher Switzer, LISCB

  11.15   "Structure-based design and synthesis of macrocyclic ligands as novel galectin-3 inhibitors” – Fredrik Sjövall, Lund University

  11.35    Common discussion on potential collaboration opportunities, joint grant applications, students

  12:00    Lunch @ LINXS

  13:00    Transfer to ESS

  13:30    Site visit (safety induction, PPE, walk to labs, experimental halls)

  15:45    Afternoon coffee/tea @ ESS

  16:15    Leave ESS

  18:00   Dinner at LINXS

  4 September

  9:00    "Small Molecules for Chemical Biology Applications" – Prof. Steve Bull, LISCB (remote presentation)

  9:30    "Understanding the RAS signalling under physiological conditions" – Dr. Kayoko Tanaka, LISCB

  10:00   "Developing small molecule inhibitors to overcome apoptosis resistance" –Dr Joanna Fox, LISCB

  10:30   Morning coffee/fika

  11:00    Common discussion on potential collaboration opportunities, joint grant applications, students

  11:45    Close-out, next steps, planning for next meeting/event

  12:00    Lunch @ LINXS and departure

• Organisers

  For questions about the agenda, please contact the organisers:

  Zoë Fisher, ESS zoe.fisher@ess.eu

  Dr James Hodgkinson, University of Leicester jthodgkinson@leicester.ac.uk

  For practical questions about the conference, please contact shandana.mufti@linxs.lu.se

Please note that we have a no-show fee of 200 SEK (for physical participation).

If you don’t receive a registration confirmation please check your spam mail.

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