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Antibodies in Solution: a LINXS - NIST Webinar Series with Margarita Kruteva - IPDD theme

When: 13 June, 2024, 15:30 - 16:30 CET

Speaker: Margarita Kruteva, FZ Jülich, Germany

Title: Diffusion NMR to study dynamics of polymers and bio-macromolecules

Abstract

Diffusion NMR complements quasielasic neutron scattering (QENS) technique at tens to hundreds millisecond time scale covering the length scale of order of a few micrometers. One of the most powerful techniques is the pulsed field gradient (PFG) NMR providing the self-diffusion constant. In my talk I will present a few examples of synergy of QENS and PFG NMR to study the polymeric and bio-macromolecular systems. In particular, the diffusion of the monoclonal Antibodies in a complex environment will be addressed.

Bio

Margarita Kruteva received her PhD in Physics in 2003 from Kazan State University, Russia. From 2005 she worked as a postdoc at the University of Leipzig on exchange processes in nanoporous materials using PFG NMR.  At the Research Centre Jülich (FZJ) she started as EU sponsored postdoc studying dynamics of polymers confined in nanoporous materials using high resolution neutron spectroscopy. From 2013 Margarita Kruteva is a senior scientist at the Jülich Centre for Neutron Science (JCNS). Her research interest focuses on structure and dynamics of polymers and complex macromolecular systems.


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