30–31 May 2024, the Chemistry of Life theme at LINXS will organise a postgraduate/postdoc symposium for young researchers.

The event will take place in Lund, Sweden, and is organised by postgraduate students from Leicester University, UK. The symposium will focus on introducing different techniques and different biological problems. We will network and identify how our research groups could work together. The meeting will be a unique experience and excellent training in multidisciplinary science. Welcome!

When: 30–31 May, 2024. Lunch-to-lunch including evening buffet at LINXS on the 30/5.

Where: at LINXS in Lund, Sweden (Scheelevägen 19, Lund), Workshop room on the 5th floor.

Organisers: Chemistry of Life Theme at LINXS, Leicester Institute of Structural and Chemical Biology second-year PhD students.

Abstract deadline: 15 March 2024 - will be extended! You are still welcome to submit your abstract.

Description

A Leicester postgraduate students-organised event to meet and discuss research with their counterparts from Lund, and wider afield. We will network and identify how our research groups could work together to tackle complex problems in the life sciences and hope to spearhead collaborations between research groups in the UK and Europe. The meeting will also be a unique experience and excellent training in multidisciplinary science.

There will be opportunities to submit an abstract for oral (limited number) or poster presentations.

There will be 3 sessions, including:

• Structure, function and dynamics of macro-molecular complexes

• The role of metals and small molecules in biology

• Chemical biology

Preliminary Programme

Programme is subject to change.

May 30

09:00-12:00: Tour around MAX IV

12:00–13:00 Lunch and networking at LINXS

13:00–13:05 Welcome to the event (Mae James, University of Leicester)

13:05–13:45 Session 1: Chemical Biology (Chair – Kelsey Hipwell)

13:05–13:25 Tom Wright – Using CRISPR/Cas9 technology and PROTACs to enable targeted protein degradation to allow functional investigations into macro-molecular protein complexes through genomic, proteomic and other readout methods

13:25–13:45 Ahmad Reza – Dynamics and interactions in entangled nanofibre dispersion

13:45–15:00 Coffee break and poster session

15:00–16:00 Session 2: The Role of Metals and Small Molecules in Biology (Chair – Jai Mercado)

15:00–15:25 Mae James – The regulatory role of haem on the transcription-translation feedback loop driving the circadian clock

15:25–15:45 Abilasha Balakrishnan – Capturing enzymes in action: molecular movies of indoleamine 2,3-dioxygenase (IDO1) by time-resolved serial X-ray crystallography and molecular modelling

15:45–16:00 Helena Bland, PhD – Technical Sales Specialist, Quorum – Advancing cryo sample preparation techniques using Quorum’s PP3010 system

16:00 Poster session, mingle and dinner buffet

May 31

10:30 Session 3: Structure, Function & Dynamics of Macro-molecular Complexes (Chair – Maha Abbas)

10:30–10:50 Thomas Allport – Understanding drug resistance in Mycobacterium tuberculosis through cryo-EM

10:50–11:10 Hannah Tompkins – Biophysical and structural approaches to study the components of a conserved Asp-sensing complex in Actinobacteria

11:10–11:30 Zehui Dong – Structure and function investigation of a lipase for plant-based fat and oil industry

11:30–11:50 Chloe Hall – Using cryo-electron microscopy (cryo-EM) to study the Ku70/80 interactome and its relationship to nucleosomes

11:50–13:00 Lunch and goodbyes

Contact

For practical questions, please contact shandana.mufti@linxs.lu.se

Organisers:
Mae James, Chair of the organising committee, and doctoral candidate mej8@leicester.ac.uk

Tennie Videler, Manager of the Institute for Structural & Chemical Biology and advisor to the organising committee hv33@leicester.ac.uk

Postgraduate students (organising committee) at Leicester Institute of Structural and Chemical Biology

The event is kindly sponsored by:

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